The LHC based μ\mup colliders

Construction of muon collider or dedicated muon ring tangential to the LHC will give opportunity to handle $\mu$p collisions at multi-TeV center of mass energies. Main parameters and physics search potential of the LHC based $\mu$p colliders are discussed.Comment: 3 pages, 3 table

Probing small x(g) region with the LHeC based gamma-p colliders

Potential of the LHeC for probing small x(g) region via c\bar{c} and b\bar{b} production have been investigated. Obtained results clearly show the advantage of gamma-p collider option. Measurement of x(g) down to 3\times10^{-6} seems to be reachable which is two order smaller than HERA coverage.Comment: 7 pages, 18 figures, 5 table

Majorana Neutrino and WRW_{R} at TeV scale epep Colliders

Production of heavy Majorana neutrino $N_{e}$ predicted by left-right symmetric extension of the Standard Model at future {\normalsize TeV} scale $ep$ colliders have been considered. In order to estimate potential of $ep$ colliders for $N_{e}$ search we consider back-groundless process $e^{-}p\rightarrow e^{+}X$ which is consequence of Majorana nature of $N_{e}$. It is shown that {\normalsize linac-LHC} and {\normalsize linac-FCC} based $ep$ colliders will cover much wider regions of $N_{e}$ and $W_{R}$ masses than corresponding linear electron-positron colliders.Comment: 14 pages, 9 figure

A Minimal Fermion-Scalar Preonic Model

A minimal fermion-scalar preonic model containing two fermionic and one scalar preons is proposed. This scheme allows to prevent the occurrence of undesired SM-level particles, namely leptons and quarks with unusual electric charges. Similar to the previous FS models, color-octet leptons and color-sextet quarks, which are expected to have masses much lower than the compositeness scale, are predicted. Observation of these particles could provide first indications of preonic models. FCC (SppC) pp option will give opportunity to probe $m_{q_{6}}$ up to 48 (75) TeV and $m_{l_{8}}$ up to 15 (27) TeV within one year operation at nominal luminosity. FCC/SppC based ep and $\mu$p colliders will essentially enlarge covered mass region, namely, $m_{e_{8}}$ up to 23/27 TeV and $m_{\mu_{8}}$ up to 68/80 TeV.Comment: 6 pages, 8 table

Indirect search for color octet electron at PWFA-LC

Indirect search for color octet electron at Plasma Wake Field Accelerator- Linear Collider (PWFA-LC) has been considered. It is shown that color octet electron masses can be probed up to 17.7 TeV at PWFA-LC with three years integrated luminosity. In addition, the compositeness scale can be probed up to 38.5 TeV.Comment: 5 pages, 6 figures, 3 table

Possible discovery channel for fourth chiral family up-quark at the LHC

Resonant production of fourth chiral family up quark at the LHC via anomalous interactions have been analyzed. It is shown that search for resonances in W^{+}b final states could lead to discovery of the fourth chiral family and simultaneously determine scale of the new physics, presumabely related to the quark and lepton compositeness. Obtained results emphasize an importance of W-leading jet invariant mass analysis in search for W+jets final states at the LHC, both with and without b-tagging.Comment: 7 pages, 6 figures, 1 tabl

Main Parameters of LCxFCC Based Electron-Proton Colliders

Multi-TeV center of mass energy ep colliders based on the Future Circular Collider (FCC) and linear colliders (LC) are proposed and corresponding luminosity values are estimated. Parameters of upgraded versions of the FCC are determined to optimize luminosity of electron-proton collisions keeping beam-beam effects in mind. It is shown that L_{ep}\sim10^{32}\,cm^{-2}s^{-1} can be achieved with moderate upgrade of the FCC parameters.Comment: 11 pages, 1 figure, 7 table

Color Octet Electron Search Potential of the FCC Based e-p Colliders

Resonant production of color octet electron, e_{8}, at the FCC based ep colliders has been analyzed. It is shown that e-FCC will cover much a wider region of e_{8} masses compared to the LHC. Moreover, with highest electron beam energy, e_{8} search potential of the e-FCC exceeds that of FCC pp collider. If e_{8} is discovered earlier by the FCC pp collider, e-FCC will give opportunity to handle very important additional information. For example, compositeness scale can be probed up to hundreds TeV region.Comment: 10 pages, 10 figures, 5 tables. arXiv admin note: text overlap with arXiv:1511.05814 (Parton showering is considered in this version of the manuscript

FCC based ep and μ\mup colliders

Construction of future electron-positron colliders (or dedicated electron linac) and muon colliders close to Future Circular Collider will give opportunity to utilize highest energy proton and nucleus beams for lepton-hadron and photon-hadron collisions. In this paper we estimate main parameters of the FCC based ep and \mu p colliders.Comment: 9 pages, 1 figure, 8 table

Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions.

Metazoan development depends on tightly regulated gene expression programs that instruct progenitor cells to adopt specialized fates. Recent work found that posttranslational modifications, such as monoubiquitylation, can determine cell fate also independently of effects on transcription, yet how monoubiquitylation is implemented during development is poorly understood. Here, we have identified a regulatory circuit that controls monoubiquitylation-dependent neural crest specification by the E3 ligase CUL3 and its substrate adaptor KBTBD8. We found that CUL3KBTBD8 monoubiquitylates its essential targets only after these have been phosphorylated in multiple motifs by CK2, a kinase whose levels gradually increase during embryogenesis. Its dependency on multisite phosphorylation allows CUL3KBTBD8 to convert the slow rise in embryonic CK2 into decisive recognition of ubiquitylation substrates, which in turn is essential for neural crest specification. We conclude that multisite dependency of an E3 ligase provides a powerful mechanism for switch-like cell fate transitions controlled by monoubiquitylation